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. 2023 Mar 7;44(8):1637–1648. doi: 10.1038/s41401-023-01067-w

Table 2.

Thermodynamic parameters obtained from the ITC measurements in Fig. 2c, d.

Protein HSP90α HSP90β
N (sites) 2.19 ± 0.111 1.34 ± 0.087
KD (µM) 3.31 ± 0.876 2.13 ± 0.934
ΔH (kCal/mol) −36.4 ± 3.26 −80 ± 9.78
ΔG (kCal/mol) −7.48 −7.74
-TΔS (kCal/mol) 28.9 72.3