Table 2.
Comparison of clinical characteristics of HCC patients between preoperative CTC ≥ 2 and < 2
| Clinical characteristics | All Patients | Patients with PVTT | ||||
|---|---|---|---|---|---|---|
| CTC < 2 (N = 239) | CTC ≥ 2 (N = 77) | P | CTC < 2 (N = 15) | CTC ≥ 2 (N = 27) |
P | |
| Age, years | 0.694 | 1.000 | ||||
| ≤ 50 | 133 | 45 | 8 | 14 | ||
| > 50 | 106 | 32 | 7 | 13 | ||
| Gender | 0.560 | 0.073 | ||||
| Male | 207 | 69 | 15 | 21 | ||
| Female | 32 | 8 | 0 | 6 | ||
| HBsAg | 0.409 | 0.123 | ||||
| Negative | 44 | 18 | 1 | 8 | ||
| Positive | 195 | 59 | 14 | 19 | ||
| Liver cirrhosis | 0.467 | 0.485 | ||||
| No | 64 | 24 | 3 | 9 | ||
| Yes | 175 | 53 | 12 | 18 | ||
| Child–Pugh score | 0.607 | 0.639 | ||||
| A | 224 | 71 | 14 | 23 | ||
| B | 15 | 6 | 1 | 4 | ||
| No. of tumor | 0.067 | 1.000 | ||||
| Single | 187 | 52 | 10 | 18 | ||
| Multiple | 52 | 25 | 5 | 9 | ||
| Largest tumor size, | 0.000 | 0.012 | ||||
| ≤ 5 cm | 117 | 9 | 4 | 0 | ||
| > 5 cm | 122 | 68 | 11 | 27 | ||
| Edmondson grade | 0.064 | 0.754 | ||||
| I-II | 147 | 38 | 7 | 11 | ||
| III-IV | 92 | 39 | 8 | 16 | ||
| AFP, ng/mL | 0.107 | 0.744 | ||||
| Low (< 400) | 153 | 41 | 7 | 10 | ||
| High (≥ 400) | 86 | 36 | 8 | 17 | ||
| BCLC stage | 0.000 | / | ||||
| 0-A | 101 | 6 | 0 | 0 | ||
| B + C | 138 | 71 | 15 | 27 | ||
| PVTT | 0.000 | / | ||||
| No | 225 | 49 | 0 | 0 | ||
| Yes | 14 | 28 | 15 | 27 | ||