Table 4.

Univariate and multivariate Cox proportional regression analysis of factors associated with OS and DFS in patients selected in the PSM model (N = 82)

Variables	Overall survival				Disease-free survival
	Univariate analysis		Multivariate analysis		Univariate analysis		Multivariate analysis
	HR (95% CI)	P	HR (95% CI)	P	HR (95% CI)	P	HR (95% CI)	P
Age, > 50 years vs ≤ 50 years	1.422 (0.792–2.552)	0.238			1.122 (0.647–1.945)	0.682
Gender, male vs female	1.647 (0.793–3.420)	0.181			1.372 (0.668–2.819)	0.389
HBsAg, positive vs negative	0.578 (0.303–1.102)	0.096			0.767 (0.409–1.441)	0.411
Liver cirrhosis, yes vs no	1.201 (0.608–2.371)	0.597			0.937 (0.506–1.734)	0.836
Child–Pugh score, B vs A	0.684 (0.245–1.911)	0.469			0.542 (0.195–1.505)	0.240
Edmonson stage, III-IV vs I-II	1.664 (0.910–3.041)	0.098			1.347 (0.771–2.353)	0.296
No. of tumors, multiple vs single	1.530 (0.841–2.784)	0.164			1.687 (0.960–2.964)	0.069
Largest tumor size, > 5 vs ≤ 5 cm	1.640 (0.508–5.294)	0.408			2.066 (0.643–6.641)	0.223
AFP, ≥ 400 vs < 400 ng/mL	1.302 (0.712–2.380)	0.392			1.680 (0.945–2.988)	0.077
BCLC stage, B-C vs 0-A	21.320 (0.020–22,572.489)	0.389			21.436 (0.037–12,308.272)	0.344
PVTT, yes vs no	7.448 (3.581–15.490)	0.000	5.619 (2.413–13.087)	0.000	4.879 (2.610–9.119)	0.000	3.890 (1.814–8.342)	0.000
Preoperative CTCs, ≥ 2 vs < 2	5.940 (3.152–11.197)	0.000	3.737 (1.660–8.412)	0.001	4.974 (2.757–8.973)	0.000	2.465 (1.139–5.334)	0.022