Table 5.

Univariate and multivariate Cox proportional regression analysis of factors associated with OS and DFS in patients with PVTT (N = 42)

Variables	Overall survival				Disease-free survival
	Univariate analysis		Multivariate analysis		Univariate analysis		Multivariate analysis
	HR (95% CI)	P	HR (95% CI)	P	HR (95% CI)	P	HR (95% CI)	P
Age, > 50 years vs ≤ 50 years	1.144 (0.593–2.208)	0.687			1.058 (0.553–2.024)	0.864
Gender, male vs female	1.854 (0.763–4.504)	0.173			1.841 (0.757–4.473)	0.178
HBsAg, positive vs negative	0.932 (0.447–1.945)	0.775			1.063 (0.485–2.331)	0.878
Liver cirrhosis, yes vs no	0.751 (0. 360–1.566)	0.852			0.847 (0.416–1.727)	0.649
Child–Pugh score, B vs A	1.298 (0.453–3.715)	0.627			0.972 (0.343–2.753)	0.958
Edmonson stage, III-IV vs I-II	1.784 (0.909–3.502)	0.092			1.407 (0.728–2.718)	0.310
No. of tumors, multiple vs single	0.981 (0.497–1.936)	0.955			1.331 (0.679–2.611)	0.405
Largest tumor size, > 5 vs ≤ 5 cm	2.992 (0.708–12.646)	0.136			3.296 (0.783–13.876)	0.104
AFP, ≥ 400 vs < 400	1.424 (0.718–2.826)	0.312			2.154 (1.082–4.291)	0.029	2.846 (1.149–7.053)	0.024
Preoperative CTCs, ≥ 2 vs < 2	3.932 (1.798–8.597)	0.001	5.162 (1.888–14.109)	0.001	2.870 (1.358–6.063)	0.006	2.499 (1.020–6.123)	0.045