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. 2023 Apr 8;149(10):8117–8129. doi: 10.1007/s00432-023-04735-w

Table 2.

Patient demographics

	Mulvihill et al. (2001)	Hecht et al. (2003)	Lee et al. (2020)	Barton et al. (2021)	Bazan-Peregrino et al. (2021)	Garcia-Carbonero et al. (2022)
	Mulvihill et al. (2001)	Hecht et al. (2003)	Lee et al. (2020)	Barton et al. (2021)	Bazan-Peregrino et al. (2021)	Part 2	Part 3
Number of patients	23	21	9	12	8	12	14
Median age (range)	66.5 (33–79)	63 (34–78)	68 (49–71)	68 (55–84)	NR (50–70 +)	60 (35–75)	66 (49–86)
Female: male (%)	27:73	43:57	56:44	75:25	25:75	42:58	64:36
Mean ECOG^a score	Range 0.00–2.00^b	0.50^b	0.33	0.50	0.63	0.67	0.57
% with locally advanced disease	35	43	100	0	25	17	14
% with distant metastases	65	57	0	100	75	83	86
Mean tumour volume (range) (cm³)	18 (4–36)	NR	NR	22 (6–57)	NR	NR	NR
Median longest tumour diameter (cm)	NR^c	NR	4.0	3.3	NR	NR	NR

^aECOG, Eastern Cooperative Oncology Group

^bConverted from Karnofsky Performance Status Scores

^cNR not reported