Table 7.
Patient responses in the clinical trials that used RECIST V.1.1 criteria
| Lee et al. (2020) | Bazan-Peregrino et al. (2021) | Garcia-Carbonero et al. (2022) | ||||
|---|---|---|---|---|---|---|
| Part 2 | Part 3 | |||||
| Dose (viral particles) | 1011 | 3 × 1011 | 1012 | All | All | All |
| Total follow-up duration | 6.5 months | 31 + months | 48 + months | 29.6 + months | ||
| Timing of CT evaluations | 12 weeks and 6.5 months | Every 8 weeks | Every 8 weeks | |||
| Complete response (%) | 0.0 | 0.0 | 0.0 | 0.0 | 8.3 | 0.0 |
| Partial response (%) | 0.0 | 33.3 | 0.0 | 12.5 | 33.3 | 42.9 |
| Stable disease (%) | 100.0 | 33.3 | 66.6 | 75.0 | 41.7 | 42.9 |
| Progressive disease (%) | 0.0 | 33.3 | 33.3 | 0.0 | 0.0 | 0.0 |
| Not evaluable (%) | 0.0 | 0.0 | 0.0 | 12.5 | 16.7 | 14.3 |