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. 2023 Apr 8;149(10):8117–8129. doi: 10.1007/s00432-023-04735-w

Table 7.

Patient responses in the clinical trials that used RECIST V.1.1 criteria

Lee et al. (2020) Bazan-Peregrino et al. (2021) Garcia-Carbonero et al. (2022)
Part 2 Part 3
Dose (viral particles) 1011 3 × 1011 1012 All All All
Total follow-up duration 6.5 months 31 + months 48 + months 29.6 + months
Timing of CT evaluations 12 weeks and 6.5 months Every 8 weeks Every 8 weeks
Complete response (%) 0.0 0.0 0.0 0.0 8.3 0.0
Partial response (%) 0.0 33.3 0.0 12.5 33.3 42.9
Stable disease (%) 100.0 33.3 66.6 75.0 41.7 42.9
Progressive disease (%) 0.0 33.3 33.3 0.0 0.0 0.0
Not evaluable (%) 0.0 0.0 0.0 12.5 16.7 14.3