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. 2023 Mar 15;149(10):7319–7326. doi: 10.1007/s00432-023-04681-7

Table 3.

Proportion of breast cancer patients with Stage IV among all breast cancer patients differentiated by HR status

Region Proportion of patients with metastases among all breast cancer patients (%) Proportion of Stage IV breast cancer patients with positive HR status with metastases among all breast cancer patients (%) Proportion of Stage IV breast cancer patients with negative HR status with metastases among all breast cancer patients (%) P value
Bone
 Europe 60.8 66.7 41.5  < 0.001
 Asia 50.5 54.4 42.3  < 0.001
 Latin America 61.3 66.4 45.0  < 0.001
Lung
 Europe 29.8 26.6 40.0  < 0.001
 Asia 38.7 38.8 38.5  < 0.001
 Latin America 35.1 31.4 47.0  < 0.001
Skin
 Europe 5.8 6.0 5.0 0.015
 Asia 3.6 3.3 4.4 0.155
 Latin America 5.6 5.2 6.9 0.155
Liver
 Europe 29.6 25.2 44.0  < 0.001
 Asia 32.2 28.9 39.2  < 0.001
 Latin America 30.7 27.0 42.3  < 0.001
Brain
 Europe 3.2 2.5 5.5  < 0.001
 Asia 4.3 3.8 5.5 0.049
 Latin America 3.8 2.1 9.2  < 0.001