Table 2.
Resection rates (CRET, complete 5-ALA, STR, resection stopped due to mapping findings); neurological deficit at day 1 and day 90
| Series | CRET | STR | Extent of resection | Fluorescence present | Complete 5-ALA resection | Surgery stopped due to mapping findings | Preoperative neurological deficit | Neurological decline POD1 | Persistent neurological deficit at day 90 | Intraoperative seizure |
|---|---|---|---|---|---|---|---|---|---|---|
| Feigl et al. [21] (2010) | 16/25 | 9/25 | NR | 25/25 | NR | 6/25 | 13/25 | 3/25 | NR | 0/25 |
| Della Puppa et al. [18] (2013) | 29/31 | 2/31 | Over 90% all cases | 31/31 bright | 23/31 | 8/31 (all had bright residual) | 6/31 | 19/31 | 2/31 | 1/31 |
| Pastor et al. [21] (2013) | 24/36 | 12/36 | 90.4% + / − 3.7% | NR | 32/36 | 4/36 | 11/36 | 6/36 | 0/36; 10 improved, 26 stable | NR |
| Schucht et al. [20] (2014) | 49/67 (73%) | 18/67 (27%) | 66/67 > 95% | 67/67 | 38/67 (57%) | 16/67 (still 9/16 had complete CRET) | 22/67 | 20 /67 (30%) | 3/67 (4%) | 1/67 (1%) |
| Goryaynov et al. [17] (2022) | 18/24 (10 did not have immediate post-op MRI) | 3/24 STR, 3/24 partial resection | NR |
IV: 14/16 III: 2/7 II: 4/11 |
28/34 | 6/34 | NR | 20/34 | 5/34 | 0/34 |
| Muscas et al. [19] (2022) | 41/65 | 24/65 | Over 90% all cases | 65/65 bright. In motor areas – 10 had none, 16 bright, 39 vague | 7/65; 17 bright residual, 41 faint residual | 16/65 (9 still had CRET) | 47/65 | 1/65; 36 improved, 28 stable | NR | NR |
CRET complete resection of enhancing tumor, STR subtotal resection, NR not reported