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. 2023 Jul;29(4):239–253. doi: 10.1192/bja.2022.3

TABLE 1.

Digital technologies to support adolescents with depression and anxiety

Digital programme (reference, country) Mental health difficulties and setting (e.g. clinic, school) Psychological and other theories Technological approaches and delivery Stakeholder involvement in programme development Evaluation and findings Access (based on information from authors, papers and online sources)
Structured and modular approaches
MoodGYM (Calear, 2009; Australia Depression, anxiety.
Any setting
CBT Interactive modules, workbook.
Stand-alone
Interviews/focus groups: young people Cluster RCT: 1477 school students. Reduction in levels of anxiety at 6 months (v. waiting list), effects on depressive symptoms less strong Available for free in Australia, subscription fee elsewhere: moodgym.com.au
CATCH-IT (Gladstone 2018; USA) Depression.
Community, clinics
CBT, IPT Interactive modules.
Supported
Groups/questionnaires: young people, practitioners RCT: 369 young people in primary care. Reduction in depression symptoms in both arms, but no difference (v. general health education, attention control), may prevent depressive episodes in those with subsyndromal depression Information: catchit-public.bsd.uchicago.edu
Grasp the Opportunity (Ip 2016; Hong Kong) Depression.
Schools
CBT Interactive modules.
Stand-alone
Questionnaires/focus groups/discussions: young people, parents, teachers, practitioners RCT: 257 students. Reduction in depressive symptoms at 12 months (v. anti-smoking website, attention control) Not available outside of research projects
CURB (Bansa 2018; USA) Depression.
Primary care
CBT, IPT Interactive modules.
Supported
Surveys/workshops: young people, parents, practitioners Feasibility study: challenges and successes in screening and implementing in urban ethnic minority primary care settings Information: checkbot-201623.appspot.com/index
Stressbusters (Smith 2015; Wright 2020; England) Depression.
Schools, community, clinics
CBT Interactive sessions, videos.
Stand-alone
Surveys/focus groups: young people, practitioners, designers Smith 2015: RCT of 112 young people in schools. Improvement in depression and anxiety symptoms at 6 months (v. waiting list)
Wright 2020: RCT of 139 young people from community and clinics. Improvement in both arms, but no difference at 12 months (v. self-help websites, attention control). Earlier study showed reduced depressive symptoms at 4 months
Not available outside of research projects
Think, Feel, Do (Stallard 2011; England) Depression, anxiety.
Clinics, schools
CBT Interactive sessions, videos.
Supported
Focus groups: children and young people, designers Pilot RCT: 20 young people, improvement on 7 subscales compared with improvement on 3 subscales in waiting-list control. Moderate to high satisfaction Not available outside of research projects
PST (Hoek 2012; The Netherlands) Depression, anxiety.
Schools, community
Problem-solving therapy Lessons, exercises, email support.
Supported
Adapted from PST programme for adults by authors RCT: 45 young people. Overall improvement in depression and anxiety for both arms, but no difference (v. waiting list) Not available outside of research projects
LEAP Project (Rickhi 2015; Canada) Depression, well-being.
Community, schools, clinics
Psychotherapeutic spiritual principles (e.g. gratitude, compassion) Interactive modules, videos, relaxation techniques, journal.
Stand-alone
Assignments/meetings/workshops/focus groups: young people, parents, practitioners, educators Pilot RCT: 31 young people. Reduced severity of depression (v. waiting list) Not available outside of research projects. Reformulated as BreathingRoom: breathingroom.me
iCBT (Topooco 2019; Sweden) Depression.
Community
CBT iCBT modules, assignments, reflection.
Supported
Surveys, text/oral feedback: users, practitioners RCT: 70 young people. Improvements in depression symptoms post-treatment (v. minimal attention control), sustained at 12 months Not available outside of research projects
iPDT (Lindqvist 2020; Sweden) Depression.
Schools, clinics, community
Psychodynamic psychotherapy Modules, exercises, therapist feedback.
Supported
Adapted from psychodynamic programme for adults by authors RCT: 76 young people. Reduced depression and anxiety symptoms at 6 months (v. online supportive contact) Not available outside of research projects
DAD Programme (Moeini 2019; Iran) Depression.
Schools
Social cognitive theory Modules, videos, animations, slides.
Supported
Interviews/focus group: young people RCT: 128 female students. Improved depression symptoms at 12 weeks (v. control group). Not available outside of research projects
BRAVE-ONLINE (Spence 2011; Australia) Anxiety.
Any setting
CBT Interactive sessions, animations, games.
Stand-alone and supported versions
Surveys/focus groups: CYP, practitioners RCT: 115 young people. Similar improvements in anxiety diagnoses and symptoms compared with face-to-face therapy at 12 months (and greater than waiting list) BRAVE Self-Help available free in Australia: brave4you.psy.uq.edu.au
BRAVE Therapist-Assisted not available outside research projects.
Information: brave-online.com
Cool Teens/ ChilledOut Online (Wuthrich 2012; Stjerneklar 2019; Australia) Anxiety.
Schools, community, clinics
CBT Multimedia information, activities, homework.
Supported
Questionnaires: young people Cool Teens: RCT: 43 young people. Reduced number and severity of anxiety disorders post-treatment (v. waiting list), sustained at 3 months.
ChilledOut: RCT: 70 young people. Outperformed waiting-list condition on diagnostic severity and anxiety symptoms post-treatment (sustained at 12 months)
Not available outside of research projects or centres with service agreements.
Information: chilledout.org.au
Camp Cope-A-Lot (Pryor 2021; USA) Anxiety.
Any setting
CBT Interactive sessions, animation, cartoon characters, homework.
Supported
Adapted from Coping Cat programme by authors Controlled trial: 27 CYP with anxiety and ASD. Reduced anxiety compared with digital social skills programme Information: copingcatparents.com/Camp_Cope_A_Lot
Gamification, serious games and avatars
SPARX (Merry 2012; New Zealand) Depression.
Any setting (especially primary care)
CBT Gamification, avatars.
Stand-alone
Workshops/focus groups: young people, families, clinicians, designers, cultural advisors RCT: 187 young people in primary healthcare. Not inferior to TAU (primarily face-to-face counselling) on depressive symptoms at 3 months Available online and via app stores for free in New Zealand: sparx.org.nz
The Journey (Stasiak 2014; New Zealand) Depression.
Schools
CBT Gamification, videos/animation.
Stand-alone
Workshops: young people, designers Pilot RCT: 34 students. Feasible, acceptable and reduction in depressive symptoms (v. computerised psychoeducation) Not available
SPARX-R (Perry 2017; Australia) Depression.
Schools
CBT Gamification.
Stand-alone
Interviews/focus groups: young people, families, practitioners RCT: 540 students. Reduced depression symptoms at 6 months(v. online attention control) Not available outside of research projects.
Information: sparx.org.nz
Rainbow SPARX (Lucassen 2015; New Zealand) Depression.
Schools, primary care
CBT Gamification, avatars.
Stand-alone
Questionnaires/focus groups: young people Open pilot trial: 21 sexual minority youth. Acceptable, feasible, and reduction in depressive symptoms Not available outside of research projects.
Information: sparx.org.nz
Pesky/Mindful gNATs (Tunney 2017; van der Meulen 2019; Ireland) Anxiety, depression.
Primary care, clinics
CBT, mindfulness Gamification.
Supported
Focus groups: CYP, practitioners, designers Tunney 2017: two-armed qualitative study: 93 CYP. Six themes identified, technology can offer ‘rich experience’.
van der Meulen 2019: naturalistic deployment study: 21 therapists, 95 young people. Three themes identified, supports real-world delivery
Available for licence fee (some resources free): peskygnats.com and mindfulgnats.com
Moderated group, social media and messaging
Master Your Mood Online (van der Zanden 2012; The Netherlands) Depression, anxiety.
Community
CBT Mood measure, facilitated sessions, chat function.
Supported
Adapted from face-to-face intervention and Coping with Depression course by authors RCT: 244 young people from community. Reduced depression and anxiety symptoms at 3 months (v. waiting list), sustained at 6 months. Information: gripopjedip.nl
MEMO (Whittaker 2017; New Zealand) Depression.
Schools
CBT Text messages, videos/ animations.
Stand-alone
Focus groups: young people, practitioners, mHealth experts RCT: 855 students. More from MEMO CBT group felt it helped them to be more positive and to get rid of negative thoughts (v. MEMO control). No effect on depressive symptoms Not available
Rebound/ MOST (Rice 2018; Australia) Depression.
Clinics
CBT, mindfulness, positive psychology, social support Social media-enabled platform.
Supported
Workshops/focus groups/ consultations: young people, families, professionals, writers/artists, designers Pilot study: 42 young people. Acceptable, feasible and safe Not available outside of research projects.
Information: orygen.org.au/Clinical-Care/Clinical-services/Moderated-Online-Social-Therapy
SOVA (Radovic 2018; USA) Depression, anxiety.
Clinics, community
Social support, psycho-education Moderated social media.
Supported
Interviews/focus groups: young people, parents, advocates, professionals Feasibility study: 96 young people, established feasibility and usability Available for free at: sova.pitt.edu
wisesova.pitt.edu
School-based technologies
Climate Schools (Teesson 2020; Australia) Depression, anxiety, substance misuse.
Schools
Psycho-education, CBT, harm minimisation Interactive modules, illustrated storylines.
Stand-alone (with teacher component)
Focus groups: young people, practitioners, designers Cluster RCT: 6386 students. Combined intervention led to increased knowledge and decreased anxiety symptoms at 30 months (v. health education, active control) Available to schools for free in Australia: rebranded as OurFutures ourfutures.education
Adapted materials available in UK (climateschools.co.uk) and USA (climateschools.com)
Smooth Sailing (O'Dea 2021; Australia) Depression, anxiety.
Schools
Step-wise approach:
psycho-education, CBT, school counselling
Stepped-care, interactive modules.
Supported
Surveys/interviews/focus groups: young people, counsellors, GPs, parents Cluster RCT: 1841 students. Marginal difference in help-seeking intentions at 12 weeks (v. school-as-usual control). Not widely available outside research projects.
Information: blackdoginstitute.org.au/research-projects/smooth-sailing
e-couch Anxiety and Worry programme (Calear 2016; Australia) Anxiety.
Schools
Psycho-education, CBT Interactive modules.
Stand-alone
Developed from existing programmes by researchers and practitioners, input/feedback from consumers Cluster RCT: 1767 students. Externally supported v. teacher-supported v. waiting list. No differences on mental health or well-being Available for free in Australia; with subscription fee elsewhere: ecouch.com.au
Emerging interactive and personalised technologies
Shamiri-Digital
(Osborn 2020; Kenya)
Depression, anxiety.
Schools
Growth mindset, gratitude, value affirmation Interactive exercises (single session).
Stand-alone
Feedback from recent high school graduates, authors RCT: 103 students. Reduced depressive symptoms at 2 weeks (v. study-skills control) Available for free: outside research projects.
thrive-online.shamiri.institute
Depis.Net (Anttila 2021, Finland) Depression.
Clinics, schools
Self-determination theory Sessions, exercises, mood/sleep diary, support system.
Supported
Interviews: young people, practitioners Quasi-experimental study: 151 students. No difference in health outcomes (v. control group). Encouraging results on adherence and acceptance Not available outside research projects
Quest-Te Whitianga (Christie 2019; Fleming 2019; Bevan Jones 2020a; New Zealand) Anxiety, depression.
Any setting
CBT, positive psychology, mindfulness, interpersonal skills Modular activities, gamification.
Stand-alone
Interviews/focus groups/ workshops: young people, designers, practitioners Acceptability testing: support from young people, Māori and Pasifika people and clinicians Not available outside of research projects
HABITs (Thabrew 2018; Merry 2020; New Zealand) Emotional health, substance use.
Schools, community
CBT, positive psychology, harm minimisation Different user groups: games, chatbots, intrinsic motivators; digital ecosystem.
Stand-alone
Surveys/focus groups: young people, practitioners, cultural advisors Acceptability/usability testing: young people with similar mental health needs and backgrounds had diverse preferences, including gamified and serious/simple interface Not available outside of research projects
MoodHwb (Bevan Jones 2020b; Wales) Depression.
Clinics, schools, community
Psycho-education, CBT, social support Illustrations/animations, profile builder, mood diary, goal-setting.
Stand-alone
Interviews/workshops/focus groups: young people, parents/carers, practitioners, designers Feasibility evaluation; 44 young people, 31 parents/carers. Acceptable and feasible Not available outside of research projects
Smartteen (Srivastava 2020; India) Depression.
Clinics
CBT Interactive presentation, quizzes, vignettes, diary.
Supported
Focus groups: young people, practitioners Pilot RCT: 21 young people. Feasible, acceptable and reduced depressive symptoms Not available outside research projects
Anxiety Coach (Whiteside 2019; USA) Anxiety.
Clinics
Exposure therapy Interactive activities, parent-coached.
Supported
Developed by authors Feasibility study: 4 therapists, 8 CYP. Feasible and acceptable Information: anxietycoach.mayoclinic.org/anxiety

ASD, autism spectrum disorder; CBT, cognitive–behavioural therapy; CYP, children and young people; GP, general practitioner; iCBT, internet-based cognitive–behavioural therapy; iPDT, internet-based psychodynamic psychotherapy; IPT, interpersonal psychotherapy; RCT, randomised controlled trial; TAU, treatment as usual; v., versus (compared with).