Table 2.
Atherosclerotic characteristics at CCTA in relation to hsCRP.
Characteristics | HsCRP (mg/L) | p-value | |||
---|---|---|---|---|---|
< 0.7 | 0.7–1.1 | 1.2–2.2 | ≥ 2.3 | ||
Coronary atherosclerosis | 3385 (39.5) | 2277 (41.9) | 2499 (44.9) | 2713 (46.5) | < 0.001 |
Coronary stenosis ≥ 50% | 413 (4.8) | 276 (5.1) | 340 (6.1) | 411 (7.0) | < 0.001 |
≥ 4 segments with atherosclerosis | 954 (11.1) | 657 (12.1) | 740 (13.3) | 872 (14.9) | < 0.001 |
≥ 50% stenosis in the LMCA, proximal LAD or 3VD | 155 (1.8) | 109 (2.0) | 123 (2.2) | 159 (2.7) | < 0.001 |
Calcified plaques | 867 (10.1) | 617 (11.4) | 682 (12.3) | 792 (13.6) | < 0.001 |
Minimally calcified plaques | 1065 (12.4) | 690 (12.7) | 778 (14.0) | 837 (14.3) | < 0.001 |
Noncalcified plaques | 676 (7.9) | 488 (9.0) | 598 (10.7) | 646 (11.1) | < 0.001 |
CAC score—degree of calcification | |||||
0—none | 5279 (62.6) | 3235 (60.6) | 3151 (57.5) | 3239 (56.2) | < 0.001 |
1–10—ultralow | 932 (11.1) | 583 (10.9) | 653 (11.9) | 693 (12.0) | < 0.001 |
11–100—low | 1348 (16.0) | 904 (16.9) | 995 (18.2) | 1040 (18.0) | < 0.001 |
101–400—moderate | 600 (7.1) | 419 (7.8) | 495 (9.0) | 515 (8.9) | < 0.001 |
> 400—high | 268 (3.2) | 198 (3.7) | 188 (3.4) | 277 (4.8) | < 0.001 |
Values are in n (%). A chi-square test was used to generate the indicated p-values.
CAC coronary artery calcium, HsCRP high-sensitivity C-reactive protein, LAD left anterior descending coronary artery, LMCA left main coronary artery, 3VD three vessel disease.