Table 7.

Effect of BP and colistin on blood biochemical parameters at 7 day post-challenge.

Treatments	AST (U/L)	ALT (U/L)	T.Pr (g/dl)	Albumin (g/dl)	Globulin (g/dl)	A/G ratio	TG (mg/dl)	Cholesterol (mg/dl)	HDL (mg/dl)	LDL (mg/dl)
Infected chickens
Control	200.57a	6.28	2.95	1.22	1.72	0.73b	49.00b	106.71	48.28	38.71
0.3 g colistin	125.71b	5.28	2.95	1.58	1.42	1.06a	61.00a	127.57	57.28	46.71
0.4 g colistin	133.29b	5.42	3.20	1.35	1.68	0.89ab	50.00b	123.28	49.14	54.14
1.0 g BP	155.14b	5.57	2.85	1.25	1.64	0.77ab	56.71ab	111.14	52.28	36.71
1.5 g BP	151.29b	5.57	3.04	1.30	1.62	0.87ab	57.71ab	112.14	53.57	36.00
SEM	7.607	0.543	0.117	0.095	0.092	0.070	2.678	5.502	2.532	6.420
P-value1
Trt	< 0.000	0.732	0.335	0.089	0.213	0.026	0.013	0.057	0.113	0.234
C vs BP	0.000	0.361	0.966	0.689	0.393	0.253	0.028	0.300	0.242	0.722
Lin	0.000	0.387	0.784	0.635	0.398	0.163	0.031	0.299	0.231	0.714
Quad	0.219	0.762	0.362	0.880	0.862	0.564	0.594	0.865	0.904	0.977
Exposed chickens
Control	152.14	6.42a	2.84	1.20	1.64a	0.76b	68.14	123.14	53.71	45.71
0.3 g colistin	143.42	4.00b	2.63	1.30	1.22b	1.10a	53.71	122.57	51.85	49.42
0.4 g colistin	148.00	5.28ab	3.02	1.40	1.63a	0.90ab	61.86	106.28	45.00	31.14
1.0 g BP	149.71	5.57ab	2.85	1.31	1.46ab	0.94ab	56.28	119.28	50.71	46.71
1.5 g BP	145.00	5.00ab	2.88	1.41	1.43ab	1.00ab	54.71	112.92	44.57	47.14
SEM	3.186	0.462	0.099	0.065	0.095	0.067	4.796	5.019	5.211	5.226
P-value1
Trt	0.324	0.015	0.123	0.162	0.026	0.019	0.205	0.114	0.642	0.597
C vs BP	0.233	0.086	0.822	0.021	0.119	0.008	0.051	0.302	0.435	0.739
Lin	0.148	0.064	0.782	0.011	0.121	0.007	0.055	0.218	0.339	0.741
Quad	0.562	0.883	0.912	0.672	0.769	0.779	0.643	0.666	0.694	0.948

0.3 g colistin: 0.3 g/kg colistin in diet; 0.4 g colistin: 0.4 g/kg colistin in diet; 1 g BP: 1 g/kg bacteriophage in diet; 1.5 g BP: 1.5 g/kg bacteriophage in diet.

AST aspartate aminotransferase, ALT alanine transaminase, T.Pr total protein, A/G albumin to globulin ratio, TG triglyceride, HDL high-density lipoprotein, LDL low-density lipoprotein.

^abValues within a column followed by different superscripts are significantly different. P < 0.05; Tukey's pairwise test.

¹Trt: overall effects of treatments; C vs BP: contrasting birds not treated with BP or colistin versus birds treated with BP; Lin: linear effects of increasing inclusion levels of BP; Quad: quadratic effects of increasing inclusion levels of BP.