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. 2023 Jul 14;14:1232285. doi: 10.3389/fphar.2023.1232285

TABLE 3.

Number and mean serum 25(OH)D concentrations of patients by chapters of the International Statistical Classification of Diseases and Related Health Problems.

ICD-10 chapter (code) Serum 25(OH)D concentration (nmol/L)
<30 30–49 50–125 >125
Number of patients (mean serum 25(OH)D concentration—nmol/L) [OR(95% CI)]
Certain infectious and parasitic diseases (A00–B99) 17 (3.66) [0.67(0.18–1.15)] 94 (20.22) [0.9(0.68–1.13)] 333 (71.61) [1.11(0.9–1.31)] 21 (4.52) [1.38(0.94–1.82)]
Neoplasms (C00–D48) 60 (5.11) [0.95(0.69–1.21)] 213 (18.14) [0.79(0.64–0.94)]* 832 (70.87) [1.07(0.94–1.2) 69 (5.88) [1.86(1.6–2.1)]*
Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50–D89) 47 (5.04) [0.94(0.64–1.23)] 180 (19.29) [0.85(0.69–1.02)] 674 (72.24) [1.15(1.0–1.29)] 32 (3.43) [1.03(0.68–1.39)]
Endocrine, nutritional, and metabolic diseases (E00–E90) 224 (4.44) [0.8(0.66–0.94)]* 1,006 (19.94) [0.88(0.8–0.95)]* 3,656 (72.47) [1.18(1.11–1.24)]* 159 (3.15) [0.94(0.77–1.11)]
Mental and behavioral disorders (F00–F99) 8 (9.09) [1.77(1.04–2.5)]* 18 (20.45) [0.92(0.4–1.44)] 57 (64.77) [0.81(0.37–1.25)] 5 (5.68) [1.76(0.85–2.66)]
Diseases of the nervous system (G00–G99) 118 (4.31) [0.79(0.6–0.98)]* 473 (17.29) [0.73(0.63–0.84)]* 2025 (74.04) [1.27(1.18–1.36)]* 119 (4.35) [1.35(1.16–1.54)]*
Diseases of the eye and adnexa (H00–H59) 6 (5.31) [0.99(0.17–1.81)] 16 (14.16) [0.59(0.06–1.12)] 85 (75.22) [1.34(0.91–1.76)] 6 (5.31) [1.63(0.81–2.46)]
Diseases of the ear and mastoid process (H60–H95) 2 (2.90) [0.53(0–1.93)] 15 (21.74) [0.99(0.42–1.56)] 50 (72.46) [1.16(0.63–1.69)] 2 (2.90) [0.87(0–2.28)]
Diseases of the circulatory system (I00–I99) 362 (6.25) [1.21(1.09–1.32)]* 1,349 (23.28) [1.1(1.03–1.16)]* 3,921 (67.67) [0.91(0.85–0.97)]* 162 (2.80) [0.82(0.65–0.98)]*
Diseases of the respiratory system (J00–J99) 31 (2.99) [0.54(0.18–0.9)]* 237 (22.88) [1.06(0.91–1.21)] 738 (71.24) [1.09(0.96–1.23)] 30 (2.90) [0.87(0.5–1.23)]
Diseases of the digestive system (K00–K93) 148 (4.71) [0.86(0.69–1.03)] 616 (19.59) [0.86(0.77–0.95)]* 2,286 (72.69) [1.18(1.1–1.27)] 95 (3.02) [0.9(0.69–1.11)]
Diseases of the skin and subcutaneous tissue (L00–L99) 39 (5.95) [1.12(0.79–1.45)] 148 (22.60) [1.04(0.86–1.23)] 451 (68.85) [0.97(0.81–1.14)] 17 (2.60) [0.77(0.29–1.26)]
Diseases of the musculoskeletal system and connective tissue (M00–M99) 280 (5.35) [1.0(0.87–1.13)] 1,049 (20.03) [0.88(0.81–0.95)]* 3,722 (71.08) [1.09(1.03–1.16)]* 185 (3.53) [1.07(0.92–1.23)]
Diseases of the genitourinary system (N00–N99) 670 (9.08) [2.05(1.96–2.15)]* 1,783 (24.17) [1.17(1.11–1.23)]* 4,718 (63.96) [0.74(0.69–0.79)]* 206 (2.79) [0.81(0.66–0.96)]*
Pregnancy, childbirth, and the puerperium (O00–O99) 4 (5.26) [0.98(0–1.99)] 11 (14.47) [0.6(0–1.24)] 60 (78.95) [1.65(1.1–2.2)] 1 (1.32) [0.39(0–2.36)]
Certain conditions originating in the perinatal period (P00–P96) 3 (6.52) [1.23(0.06–2.4)] 19 (41.30) [2.52(1.93–3.1)]* 18 (39.13) [0.28(0–0.87)] 6 (13.04) [4.38(3.52–5.24)]*
Congenital malformations, deformations, and chromosomal abnormalities (Q00–Q99) 5 (2.99) [0.54(0–1.44)] 29 (17.37) [0.75(0.35–1.15)] 124 (74.25) [1.27(0.92–1.62)] 9 (5.39) [1.66(0.99–2.34)]
Symptoms, signs, and abnormal clinical and laboratory findings, not classified elsewhere (R00–R99) 181 (4.90) [0.9(0.75–1.06)] 832 (22.54) [1.04(0.96–1.12)] 2,562 (69.39) [1.0(0.92–1.07)] 117 (3.17) [0.95(0.76–1.14)]
Injury, poisoning, and certain other consequences of external causes (S00–T98) 1 (1.27) [0.23(0–2.2) 12 (15.19) [0.64(0.02–1.25)] 64 (81.01) [1.88(1.32–2.44)]* 2 (2.53) [0.76(0–2.16)]
Codes for special purposes (U00–U85) 0 (0.00) [N/C] 6 (33.33) [1.79(0.81–2.77)] 11 (61.11) [0.69(0–1.64) 1 (5.56) [1.71(0–3.73)]
Sine morbo (U9990) 115 (1.96) [0.32(0.13–0.51)] 1,549 (26.35) [1.33(1.27–1.39)]* 4,023 (68.44) [0.95(0.89–1.01)] 191 (3.25) [0.97(0.82–1.13)]
Unknown 121 (6.93) [1.33(1.14–1.52)]* 312 (17.87) [0.77(0.65–0.89)]* 1,234 (70.68) [1.06(0.96–1.17)] 79 (4.52) [1.4(1.17–1.63)]*

Bold: above the mean; *, statistically significant; N/C, not computable.