. 2023 Jun 12;10(4):2541–2549. doi: 10.1002/ehf2.14420

Table 2.

C‐statistic analysis of t‐PA as predictors for primary endpoint

	Total cohort (n = 347)	AVSc (n = 183)	Non‐AVSc (n = 164)
AUC‐ROC (T‐PA only)	0.709 (0.650–0.768)	0.753 (0.682–0.823)	0.561 (0.442–0.681)
AUC‐ROC (T‐PA only)	P < 0.001	P < 0.001	0.301
AUC‐ROC (Traditional factors only)	0.657 (0.595–0.719)	0.679 (0.599–0.759)	0.581 (0.466–0.697)
AUC‐ROC (Traditional factors only)	P < 0.001	P < 0.001	0.171
AUC‐ROC (Traditional factors + t‐PA)	0.750 (0.693–0.806)	0.846 (0.789–0.904)	0.581 (0.466–0.697)
AUC‐ROC (Traditional factors + t‐PA)	P < 0.001	P < 0.001	0.171
NRI	0.493 (0.272–0.714)	0.857 (0.590–1.124)	0.165 (−0.236–0.566)
NRI	P < 0.001	P < 0.001	0.419
IDI	0.096 (0.064–0.128)	0.217 (0.156–0.277)	0.027 (−0.006–0.061)
IDI	P < 0.001	P < 0.001	0.106

Traditional factors included age, sex, BMI, smoking, alcohol use, history of DM, history of hypertension, HbA1c, TG, TC, HDL, LDL, rGT, eGFR, aspirin use, ACEI/ARB use, beta‐blocker use, and statin use.