Table 1.

Potential strategies for intercurrent events

Strategy	Relevant values for patients with the intercurrent event
Treatment policy	Actual values of the variable regardless of whether the intercurrent event has occurred
Composite	Modified definition of the variable incorporating the intercurrent event
Hypothetical	Values the variable would have taken in the hypothetical scenario envisaged in which the intercurrent event would not occur
While on-treatment/at-risk	Values of the variable up to the time of the intercurrent event
Principal stratum	Restrict population to patients who would not experience the intercurrent event