FIGURE 4.

PGE₂ levels in sham colon and different colonic sites of Crohn’s-like colitis. Full-thickness colon tissues were taken for the measurements of PGE₂. Shown are PGE₂ levels in sham and different sites (P, I, and D) of TNBS colitis (day 7) with regular diet (solid bar) and liquid diet treatment (streaked bar). Note: PGE₂ levels were significantly increased in site P and I, but not in site D of CD-like rats. Liquid diet treatment blocked PGE₂ increase in the P-site. N = 5 or 6. *p < 0.05 vs. sham. #p < 0.05 vs. I-site/regular food.