Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2023 Jul 14;14:1215900. doi: 10.3389/fphys.2023.1215900

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2023 Johnson, Geesala, Zhang, Lin, M’Koma and Shi.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Effect of NS-398 treatment on body weight change and inflammation index in Crohn’s-like colitis rats. NS-398 (5 mg/kg, i. p. daily) and vehicle control (DMSO saline) were administered daily to sham and TNBS-induced Crohn’s-like colitis rats. The percentage changes of body weight over 7 days of treatment (after TNBS instillation and vehicle or NS-398 treatment) were determined (A). The inflammation index (1–3) was scored (B) on the day when animals were euthanized, and the colon was taken out. N = 4 or 5 rats. p values are given for the comparisons. S, sham; T, TNBS treated rats (Crohn’s-like colitis); Veh, vehicle.