Table 1.
Patient Demographics.
| Total population | Younger group | Older group | p-value | ||
|---|---|---|---|---|---|
| Number | 326 | 263 (80.67%) | 63 (19.32%) | ||
| Age (median) | 59.0 [29.0;85.0] | 54.0 [29.0;69.0] | 73.0 [70.0;85.0] | <0.001 | |
| Women |
319 (97.85%) | 258 (98.1%) | 61 (98.8%) | 0.624 | |
| Men | 7 (2.15%) | 5 (1.90%) | 2 (3.17%) | ||
| Menopause | <0.001 | ||||
| No | 82 (25.7%) | 82 (31.8%) | 0 (0.00%) | ||
| Yes | 216 (67.7%) | 155 (60.1%) | 61 (100%) | ||
| Peri | 21 (6.58%) | 21 (8.14%) | 0 (0.00%) | ||
| Relevant co-morbidities | 0.002 | ||||
| 128(39.3%) | 92 (35%) | 36 (57.1%) | |||
| CVD | 104(100%) | 71 (100%) | 33 (100%) | ||
| History of cancer* | 24(100%) | 18 (100%) | 6 (100%) | ||
| BC history | 27 (100%) | 16 (100%) | 11 (100%) | ||
| BMI | 0.147 | ||||
| <18.5 | 10 (3.17%) | 9 (3.54%) | 1 (1.64%) | ||
| 18.5–24.9 | 155 (49.2%) | 132 (52.0%) | 23 (37.7%) | ||
| 25–29.9 | 96 (30.5%) | 69 (27.2%) | 27 (44.3%) | ||
| 30–34.9 | 37(11.7%) | 29 (11.4%) | 8 (13.1%) | ||
| 35–39.9 | 12 (3.81%) | 10 (3.94%) | 2 (3.28%) | ||
| >40 | 5 (1.59%) | 5 (1.97%) | 0 (0.00%) | ||
| Positive family history* | 0.399 | ||||
| No | 236 (76.9%) | 188 (75.2%) | 48 (84.2%) | ||
| Yes | 69 (22.5%) | 60 (24%) | 9 (15.8%) | ||
| Germline mutation | 0.023 | ||||
| No | 74 (24.7%) | 68 (28%) | 6 (10.5%) | ||
| BRCA1/2 | 8 (2.67%) | 7 (2.88%) | 1 (1.75%) | ||
| Other | 11 (3.67%) | 10 (4.12%) | 1 (1.75%) | ||
| Not tested | 206 (68.7%) | 157 (64.6%) |
|
⁎
Not breast cancer **Breast cancer in first degree relatives, CVD= cardiovascular disease, BC =breast cancer, BMI=body-mass-index.