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Evaluation of Matrix-Degrading Enzymes’ gene expression in LoVo CRC cells cultured in different matrix substrates after 3 and 24 h. The gene expression of MMP-2 (A), MMP-9 (B), MMp-14 (C), and HPSE (D) in LoVo cells cultured on Matrigel and type I Collagen for 3 and 24 h was evaluated by Real-Time PCR and normalized at GAPDH as housekeeping. Graphs represent Mean ± S.D. n = 6. * p < 0.05, ** p < 0.001, *** p < 0.0001.
