Table 1.

Approved Indications of NAC: Dosage Forms and Routes of Administration.

Dosage Form	Administration Route	Dose/Strength	Medical Condition/Therapy Type	Indication
Injectable	IV	200 mg/mL (6 g/30 mL)	Poisoning/antidote	Acetaminophen overdose reduction; prevention of acute hepatic injury; hepatic injury from repeated supra-therapeutic ingestion.
Effervescent tablet	Oral	500 mg 2.5 g
Solution	Oral	10% 20%	Broncho-pulmonary disorders/Adjuvant therapy	Abnormal, viscid, inspissated mucous secretions in chronic [!] and acute [@] broncho-pulmonary disease. Pulmonary complications of cystic fibrosis; tracheostomy care; pulmonary complications associated with surgery; use during anesthesia; post-traumatic chest conditions; atelectasis due to mucous obstruction and diagnostic bronchial studies [#]
Solution	Inhalation	10% 20%

[!] Chronic broncho-pulmonary disease: chronic emphysema, chronic emphysema with bronchitis, chronic asthmatic bronchitis, tuberculosis, bronchiectasis, and pulmonary amyloidosis of the lung. [@] Acute broncho-pulmonary disease: pneumonia, bronchitis, and tracheobronchitis. [#] Diagnostic bronchial studies: bronchograms, bronchospirometry, and bronchial wedge catheterization. This table is adapted from Šalmon et al., 2019 [26].