Figure 2.

Effect of SMM extract on apoptotic cell death in human ovarian cancer cells. Human ovarian cancer A2780 (A) and SKOV3 (B) cells were treated with SMM extract for 48 h at the indicated concentrations and stained with PI and annexin V-FITC. The bar graph indicates the percentages of annexin V-positive apoptotic cells in the right quadrants of flow cytometry results. Cisplatin (10 µM) was used as a positive control. The data are representative of three independent experiments. Data were analyzed using one-way ANOVA followed by Dunnett’s multiple comparison test. * p < 0.05 as compared with the untreated group.