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Dose conversion factors of HT doses between rats and humans.
| Humans | Mice | Rats | |
|---|---|---|---|
| HED (mg/kg) | Total Dose (mg) a | Dose (mg/kg) b | Dose (mg/kg) c |
| 10 | 600 | 140.4 | 72.2 |
| 7 | 420 | 98.3 | 50.6 |
| 1.5 | 90 | 21.1 | 10.8 |
| 0.75 | 45 | 10.5 | 5.4 |
| 0.25 | 15 | 3.5 | 1.8 |
| 0.01 | 0.6 | 0.14 | 0.07 |
a Total dose is calculated considering a standard adult of 60 kg of body weight. Reference weight was considered to be 0.02 kg for mice b and 0.15 kg for rats c. Bold corresponds to the total doses achievable with the diet.
