Table 5.
Predictors of AddiQoL score (GWS symptom burden) 12 weeks after surgical remission of hypercortisolism.
| Presurgical parameter | Univariable analysis | Multivariable analysis | ||||
|---|---|---|---|---|---|---|
| Estimate | Standard error | P-value | Estimate | Standard error | P-value | |
| Age at diagnosis (per 10-year increase) | 0.266 | 0.088 | .003 | 0.159 | 0.090 | .081 |
| Sex, female | −7.935 | 3.036 | .010 | −3.633 | 2.987 | .227 |
| Body mass index (per 1 kg/m2 increase) | −0.275 | 0.146 | .063 | 0.006 | 0.148 | .968 |
| Duration of symptoms prior to diagnosisa (per 1-month increase) | −0.028 | 0.030 | .342 | - | - | - |
| Clinical disease severity score (per 1-point increase) | −0.977 | 0.220 | <.001 | −0.689 | 0.250 | .007 |
| Sit-to-stand test performance, Z-score | 1.865 | 0.794 | .021 | 1.249 | 0.769 | .107 |
The AddiQoL score was used as a marker of GWS symptom burden. A lower AddiQoL score corresponds to higher symptom burden.
Abbreviation: GWS, glucocorticoid withdrawal syndrome.
a
Patients with mild autonomous cortisol secretion were excluded from the specific analysis.