Figure 2.

Biological activities of PIC and its analogs. (A) DPPH radical scavenging activity; (B) AChE inhibitory activities; (C) inhibitions against Aβ peptide (1–42) aggregations; (D) neuroprotection against Aβ peptide (25–35)-induced cell deaths. IC₅₀ represented the concentrations for 50% inhibition in the present study. The Aβ-induced cell deaths in SH-Y5Y cells between the control and the blank or the control and each sample treatment were analyzed using Student’s t-test, and any difference in comparison with the control group was considered statistically significant when p < 0.05 *, or p < 0.01 **, or p < 0.001 ***.