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. 2023 Jun 24;11(7):1809. doi: 10.3390/biomedicines11071809

Table 1.

Disease course and therapy of patients affected by severe combined immunodeficiencies and vaccinated with BCG. Adapted from [6].

Cohort n (%) Anti-Mycobacterial Therapy
Vaccinated patients 349 238/349 (68%)
BCG-related disease 177/349 (51%) 160/177 (90%)
   Disseminated 118/177 (34%) 107/118 (90%)
   Localized 59/177 (17%) 53/59 (89%)
No BCG-related disease 172/349 (49%) 78/172 (45%)
SCID treatment and IRIS
HSCT/GT/Thymus transplantation/ERT
(% of total patients)
184/3/1/2 (54%)
   IRIS 55/190 (29%)
   Previously symptomatic for BCG-related disease 47/55 (85%)