Table 1.
Features of macrophage composition in the kidneys in patients with fatal MI and in patients from the control group (number of positive stained macrophages counted per histology section area of interest and analyzed in 10 randomly chosen fields of view).
| Cells | All Patients (n = 30) | Control (n = 8) | p1 | Group 1 (n = 17) | Group 2 (n = 13) | p2 | p3 | p4 |
|---|---|---|---|---|---|---|---|---|
| CD163+ | 55 (32; 97) | 47 (34; 68) | 0.5 | 55 (34; 72) | 58 (32; 97) | 0.5 | 0.9 | 0.4 |
| CD68+ | 30 (23; 51) * | 41 (33;48) | 0.45 | 30 (24; 49) * | 35(23; 51) * | 0.7 | 0.4 | 0.7 |
| CD206+ | 4 (2; 6) *, ** | 30 (27; 35) | 0.0005 | 6 (5; 8)*,** | 2 (1; 2) *, ** | 0.01 | 0.005 | 0.0001 |
| Stabilin-1+ | 2 (1; 3) *, **, *** | 2 (1; 3) *, **, *** | 0.8 | 1 (1; 4) *, **, *** | 2 (1; 2) *, ** | 0.3 | 0.9 | 0.7 |
| CD80+ | 3 (2; 5) *, **, *** | 6 (6; 7) *, **, ***, **** | 0.0003 | 5 (3; 5) *, **, *** | 2 (1;2) *, ** | 0.01 | 0.0005 | 0.0007 |
Note: MI—myocardial infarction. p1—Significant difference between the group with fatal MI and the control group; p2—significant difference between patients with fatal MI from group 1 and group 2; p3—significant difference between patients with control group from group 1; p4—significant difference between patients with control group from group 2. *—Significant difference in the group between the number of CD163+ cells and other cells; **—significant difference in the group between the number of CD68+ cells and other cells; ***—significant difference in the group between the number of CD206+ cells and other cells; ****—significant difference in the group between the number of stabilin-1+ cells and other cells.