Table 3.
Serum levels of 25(OH)D and DBP in different MS phenotypes vs controls.
| Healthy Controls | Relapsing-Remitting | p a | Secondary Progressive | p b | p c | |
|---|---|---|---|---|---|---|
| All Subjects (n) | 146 | 166 | 26 | |||
| Subjects on Vitamin D supplement |
33 | 60 | 16 | |||
| 25(OH)D (nmol/L) | 28.4 (18.0–50.4) | 25.7 (16.0–47.8) | 0.387 | 45.5 (22.0–59.2) | 0.046 | 0.025 |
| DBP (µg/mL) | 236 (152–288) | 162 (123–239) | <0.001 | 194 (127–246) | 0.049 | 0.508 |
| Subjects not on Vitamin D supplement |
n = 112 | n = 101 | n = 10 | |||
| 25(OH)D (nmol/L) | 26.2 (16.7–35.0) | 22.1 (13.0–36.3) | 0.051 | 35.4 (19.4–64.7) | 0.056 | 0.029 |
| DBP (µg/mL) | 246 (161–299) | 159 (120–248) | <0.001 | 247 (222–271) | 0.801 | 0.011 |
Values are expressed by Median (25th–75th percentile). p-values are generated using Mann–Whitney U test for pairwise comparisons a Relapsing-Remitting vs. Controls; b Secondary Progressive vs. Controls; c Relapsing-Remitting vs. Secondary Progressive. Note that Numbers may not add up to the total due to missing data.