Table 2.
Epidemiological and clinical characteristics of patients treated with Sonidegib.
| PT | Age | Sex | Comorbidities | Type of BCC | Localization | N D (Larger) |
PTCH1 Mutation |
|---|---|---|---|---|---|---|---|
| 1 | 53y | M | Cleft lip and palate Longitudinal sickle calcification |
Multiple BCCs laBCC |
Head and neck Trunk and limbs Scalp |
>100 BCCs >10 BCCs 5 × 6 cm |
+ |
| 2 | 74y | F | Dyslipidemia Arterial hypertension |
La BCC | Temporal area, right ear | 10 × 9 cm | Not tested |
| 3 | 88y | M | Diverticulosis Umbilical hernia Cholecystectomy Abdominal aortic aneurysm Arterial hypertension Chronic renal failure Transient ischemic attack |
laBCC | Left ear | - | Not tested |
| 4 | 45y | F | - | Multiple BCCs laBCC |
Head and neck, trunk Right ear |
>10 BCCs >10BCCs - |
+ |
| 5 | 45y | F | - | laBCC | Right cheek and periocular | 5.3 cm | Not tested |
| 6 | 70y | M | - | laBCCs Multiple BCCs |
Scalp Head and neck |
- >7BCCs |
Not tested |
| 7 | 71y | F | Diabetes mellitus 1 Meningioma |
Multiple BCCs LaBCC |
Head and neck Scalp |
- 10 × 5 cm |
Not tested |
| 8 | 79y | M | Arterial hypertension Hypothyroidism Mild cognitive impairment |
laBCC | Right shoulder, hemithorax, and hip | - | - |
| 9 | 54y | M | Cleft lip and palate | laBCC Multiple BCCs |
Inferior eyelid + nose Head and neck |
- | + |
| 10 | 30y | F | - | Multiple BCCs laBCCs |
Head and neck Scalp |
- | + |
Legend. PT (patients); BCC (basal cell carcinoma); N (number); D (diameter); y (years); F (female); M (male).