Figure 3.

Evaluation of structures available from X-ray crystallography or AlphaFold (Table S1) for (a) CP motifs, (b) C-based motifs, (c) H-based motifs, and (d) Y-based motifs. The coordinating residues, i.e., Cys (a,b), His (c), and Tyr (d) are highlighted in red. Each figure displays selected examples of representative protein sequences (from the N-terminus (left) to the C-terminus (right)) either individually (a,c,d) to highlight the differences in the conformations or as a superimposition (b), in case no pronounced structural features were observed. Here, ‘_’ represents the residues that were not contained in the given PDB structure because of their position at the terminus. HBMs of the proteins highlighted in “grey” are not identified. Additional information concerning the conformation observed for each HBM can be found in Table S1.