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. 2023 Jul 19;13(7):1092. doi: 10.3390/brainsci13071092

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© 2023 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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The effects of treatment with BCP on the levels of CNS immunity (microglia) and systemic immunity (blood and spleen lymphocytes) in EAE mice; each column presents the effects of DMF, BCP, and the combination of AM630 and BCP on the decreased levels of anti-inflammatory/ inflammatory ratios in the spleen lymphocytes (Th₁₇/T_reg and Th₁/Th₂), blood (IL-17/IL-10), and microglia (M₁/M₂). Data were presented as Mean ± SEM. The B, T₁₇, T₁, and M₁ Abbreviations represent the ratios of blood IL-17/IL-10, Th₁₇/T_reg, Th₁/Th₂ and M₁/M₂.