Table 2.
Protocol | Groups | EAE | From Day 10 to 37 (Every Day) |
|
---|---|---|---|---|
1 (n = 8/each group) |
Sham | - | - | |
Control | ✓ | Vehicle | ||
BCP (2.5 mg/kg) | ✓ | BCP 2.5 mg/kg/day; p.o. | ||
BCP (5 mg/kg) | ✓ | BCP 5 mg/kg/day; p.o. | ||
DMF (60 mg/kg) | ✓ | DMF 30 mg/kg two times per day; p.o. | ||
2 (n = 8/each group) |
30 min later | |||
Sham | - | - | - | |
Control | ✓ | AM630 vehicle; i.p. | +BCP vehicle; p.o. | |
BCP (5 mg/kg) | ✓ | AM630 vehicle; i.p. | +BCP 5 mg/kg/day; p.o. | |
AM630 (1 mg/kg) + BCP (5 mg/kg) |
✓ | AM630 1 mg/kg/day; i.p. | +BCP 5 mg/kg/day; p.o. |