Table 2.
Pre-operative demographic, clinical and radiological features of the included cohort. EEA: extended endoscopic endonasal approach; EA: endoscopic endonasal approach; TCA: transcranial approach; DI: diabetes insipidus.
| N, % or SD | ||
|---|---|---|
| Sex | Male | 35, 61.4 |
| Female | 22, 38.6 | |
| Age | 54.1 ± 13.5 | |
| BMI | 27.8 ± 5.4 | |
| Previous treatment | Naïve | 26, 45.6 |
| Previous surgery | 30, 52.6 | |
| Previous surgery and radiotherapy | 1, 1.8 | |
| Previous surgical procedure | EEA | 20, 64.5 |
| EA + TCA | 2, 6.5 | |
| TCA | 5, 16.1 | |
| Microsurgical trans-sphenoidal | 4, 12.9 | |
| First clinical manifestation | Cognitive decline | 3, 5.3 |
| Endocrinological hyperproduction | 15, 26.3 | |
| Visual disturbances | 32, 56.1 | |
| Incidental | 6, 10.5 | |
| Headache | 1, 1.8 | |
| Endocrinological hypersecretion at admission | PRL | 5, 8.8 |
| ACTH | 4, 7 | |
| GH | 4, 7 | |
| TSH | 1, 1.8 | |
| No | 43, 75.4 | |
| Endocrinological impairment at admission | Anterior partial hypopituitarism | 1, 1.8 |
| Anterior panhypopituitarism | 14, 24.6 | |
| DI | 0, 0 | |
| Anterior partial hypopituitarism and DI | 1, 1.8 | |
| Panhypopituitarism and DI | 1, 1.8 | |
| No | 40, 70.2 | |
| Visual acuity impairment at admission | Yes | 6, 10.5 |
| No | 51, 89.5 | |
| Visual field impairment at admission | Yes | 34, 59.6 |
| No | 23, 40.4 | |
| Volume, cm3 | 13.8 ± 16.8 | |
| Maximal diameter, mm | 30.3 ± 12.8 | |
| Cranial extension | Foramina of Monro | 11, 19.3 |
| Third ventricle | 22, 38.6 | |
| Suprasellar cistern | 24, 42.1 | |
| Morphology according to Barazi et al. [21] | Type 1 | 16, 28.1 |
| Type 2 | 7, 12.3 | |
| Type 3 | 34, 59.6 | |