| TGM-2 | Transglutainase-2 |
| mAchRs | Muscarinic Cholinergic Receptors |
| TGases | Transglutaminases |
| AAALAC | American Association for Accreditation of Laboratory Animal Care |
| ARVO | Association for Research in Vision and Ophthalmology |
| IACUC | Institutional Animal Care and Use Committee |
| TGM-2-/- | Transglutaminase-2 mutant |
| mAChR1-5-/- | Muscarinic Cholinergic Receptor 1–5 mutant |
| WT | Wild-type |
| SF | Scleral Fibroblast |
| DMEM | Dulbecco’s Modified Eagle Medium |
| PMMA | Polymethylmethacrylate |
| RNA | Ribonucleic acid (RNA) |
| DNA | deoxyribonucleic acid |
| siRNA | small interfering RNA |
| ECM | Extra Cellular Matrix |
| MMP9 | Matrix Metalo Proteinase-9 |
| IC50 | Half-maximal inhibitory concentration |
| TIMP1 | Tissue Inhibitor of Metalloproteinase-1 |
| TNF-α | Tumor necrosis factor alpha |
| TNF-β | Tumor necrosis factor beta |
| PCA | Principal Component Analysis |
| EDTA | Ethylenediaminetetraacetic acid |
| qRT-PCR | quantitative Real-Time Polymerase Chain Reaction |
| GO | Gene Ontology |
| PBS | Phosphate Buffered Saline |
| RT | Room Temperature |
| IHC | Immunohistochemistry |
| SDS-PAGE | Sodium dodecyl-sulfate polyacrylamide gel electrophoresis |
| PMSF | phenylmethylsulfonyl fluoride is a serine protease inhibitor |
| RIPA buffer | Radioimmunoprecipitation assay buffer |
| TBST | Tris-buffered saline with 0.1% Tween® 20 |
| ANOVA | Analysis of Variance statistical test |