Table 3.

Average longevity of use in years of various medication classes in CRPS cases and matched controls.

Characteristic	CRPS, N = 2510 1	Control, N = 2510 1	Difference 2	95% CI 2,3	p-Value 2	q-Value 4
Medication Class
Benzodiazepines	0.76 (1.83)	0.37 (1.30)	0.3876494024	0.30, 0.48	<0.001	<0.001
Bisphosphonates	0.11 (0.67)	0.07 (0.50)	0.0342629482	0.00, 0.07	0.041	0.047
Calcitonin	0.00 (0.04)	0.00 (0.03)	0.0007968127	0.00, 0.00	0.5	0.5
Capsaicin	0.08 (0.38)	0.03 (0.22)	0.0537848606	0.04, 0.07	<0.001	<0.001
Neuropathic pain medications	4.06 (5.18)	1.35 (3.17)	2.7147410359	2.5, 3.0	<0.001	<0.001
NSAIDs	3.11 (4.25)	2.21 (3.08)	0.9051792829	0.70, 1.1	<0.001	<0.001
Opioids	3.95 (5.21)	1.30 (2.57)	2.6442231076	2.4, 2.9	<0.001	<0.001
Steroids	1.07 (1.95)	0.66 (1.43)	0.4151394422	0.32, 0.51	<0.001	<0.001
None	0.00 (0.00)	0.00 (0.00)	0.0000000000

¹ Mean (SD); ² Welch Two Sample t-test; ³ CI = Confidence Interval; ⁴ False discovery rate correction for multiple testing.