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. 2023 Jul 18;11(7):2019. doi: 10.3390/biomedicines11072019

Figure 3.

Figure 3

Niclosamide inhibits HuR nucleocytoplasmic translocation. (a–f) Western blot of HuR and CD147 in nuclear and cytoplasmic fractions with niclosamide treatment at different concentrations and different times in NL20 (a,b), H460 (c,d), and WI-38 (e,f). Quantified relative levels of cytoplasmic HuR in NL20 (as in blue box), H460 (as in red box), and WI-38 (as in green box) are shown in (a’–f’), respectively. (g) Western blot of HuR and CD147 protein in Hela, 293FT, RKO, and MDA-MB-231 cells treated with niclosamide at different concentrations. NIC, niclosamide.