Table 1.

The role of CMA in different cancers.

Type of Cancer	CMA Action Factor and Its Activity	CMA Activity	Cellular Physiological Processes	Subjects	Cancer Development	Reference
Pancreatic carcinoma	IGF-IR, Down	Up	Cell signaling	The human PC Cell lines	Inhibition	[73]
Ovarian carcinoma	HK2, Down	Up	Glucose metabolism	Cell lines	Inhibition	[48]
Breast carcinoma	HSD17B4, Down	Up	Protein modification	Breast cancer tissues	Inhibition	[52]
	ATG5, Down	Up	Gene transcription	Breast cancer Cell lines	Promotion	[70]
Hepatocellular carcinoma	HMGB1, Down	Up	Gene expression	Cell lines	Promotion	[74]
	TP53, Down	Up	Gene expression	Cell lines	Inhibition	[49]
Colorectal carcinoma	P21, Down	Up	Gene expression	CRC tissues	Promotion	[65]
Gastric carcinoma	RND3, Down	Up	Cell growth	GC tissues	Promotion	[64]
Papillary thyroid carcinoma	PPAR γ, Down	Up	Cell signaling	PTC tissues	Promotion	[72]
Glioblastoma	N-CoR, Down	Up	Protein modification	Glioma cell line U87-MG and tissues	Promotion	[60]
Lung carcinoma	N-CoR, Down	Up	Protein folding	Lung cancer cell lines	Promotion	[59]
	ErK3, Down	Up	Protein modification	Cell lines	Inhibition	[75]
	MCL1, Up	Down	Protein modification	NSCLC cell lines	Promotion	[56]
Renal carcinoma	PKM2, Up	Down	Glucose metabolism	Cell lines	Promotion	[68]
Prostate carcinoma	TPD52, Up	Down	Protein modification	C57BL/6 mouse	Promotion	[76]