Figure 1.

Guidelines for using artificial intelligence in intracranial aneurysm rupture risk assessment. # In terms of genomics, studies have mentioned that three single nucleotide polymorphisms may be associated with aneurysms [27]. * Aneurysm risk is proportionately higher in those with genetic conditions like polycystic kidney disease [28], although it is yet unclear whether the risk of rupture is also higher. $ According to a study, patients with ruptured aneurysms had considerably decreased serum vitamin D levels [29]. † The angle between the parent artery’s central axis and the aneurysm’s main axis is known as the aneurysm inflow-angle. It is a significant risk factor for the rupture of lateral wall aneurysms, according to studies [30]. SAH, subarachnoid hemorrhage; AR, aspect ratio; SR, size ratio; WSS, wall shear stress; NWSS, normalized WSS; OSI, oscillatory shear index; LSA, low WSS area; RRT, relative residence time; HR-VWI, high resolution magnetic resonance vessel wall imaging.