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Anti-Proliferation Activities of Compound Series 10 against HT-1080, RD, GCT, and MCF-7 cells.
| Compound | IC50 (nM) | |||
|---|---|---|---|---|
| HT-1080 | RD | GCT | MCF-7 | |
| 10a | > 20000 | > 20000 | > 20000 | > 20000 |
| 10b | > 20000 | > 20000 | > 20000 | > 20000 |
| 10c | > 20000 | > 20000 | > 20000 | > 20000 |
| 10d | > 20000 | > 20000 | > 20000 | > 20000 |
| 10e | > 20000 | > 20000 | > 20000 | > 20000 |
| 10f | > 20000 | > 20000 | > 20000 | > 20000 |
| 10g | > 20000 | > 20000 | > 20000 | > 20000 |
| 10h | > 20000 | > 20000 | > 20000 | > 20000 |
| FiVe1 | 1564 ± 288 | 3095 ± 555 | 1686 ± 349 | > 20000 |
