Table 4.

GLCM-based radiomic features for real and synthetic T2W for CycleGAN and DC²Anet models.

Features	Real T2W	Synthetic T2W-CycleGAN	Synthetic T2W-DC2Anet	95% CI of Diff
	Mean ± SE **	Mean ± SE	Mean ± SE	Real T2W vs. Synthetic T2W-CycleGAN	Real T2W vs. Synthetic T2W-DC2Anet
Auto Correlation	330 ± 26.40	331 ± 52.22	348 ± 49.5	−176.8 to 173.8	−194.5 to 156.1
Cluster Prominence	17,303 ± 1501	15,367 ± 1009	12,133 ± 455	−2019 to 5892	1214 to 9125 *
Cluster Shade	722.4 ± 41.14	716 ± 18.76	677.2 ± 33.74	−111.2 to 124.0	−72.39 to 162.7
Contrast	43.96 ± 0.9	42.06 ± 1.04	31.67 ± 0.86	−1.487 to 5.296	8.902 to 15.68 *
Correlation	0.005 ± 0.0004	0.0051 ± 0.0007	0.05 ± 0.0098	−0.0212 to 0.0195	−0.0703 to −0.0296 *
Energy	0.43 ± 0.01	0.44 ± 0.01	0.43 ± 0.007	−0.040 to 0.027	−0.029 to 0.037
Entropy	2.47 ± 0.08	2.4 ± 0.03	2.34 ± 0.03	−0.139 to 0.263	−0.074 to 0.328
Homogeneity	0.67 ± 0.01	0.68 ± 0.009	0.63 ± 0.007	−0.044 to 0.021	0.0052 to 0.071

* Significant difference; ** Standard error (SE).