Table 5.

GLCM-based radiomic features for real and synthetic FLAIR for CycleGAN and DC²Anet models.

Features	Real FLAIR	Synthetic FLAIR-CycleGAN	Synthetic FLAIR -DC2Anet	95% CI of Diff
	Mean ± SE	Mean ± SE	Mean ± SE	Real FLAIR vs. Synthetic FLAIR—CycleGAN	Real FLAIR vs. Synthetic FLAIR—DC2Anet
Auto Correlation	277 ± 5.69	269.6 ± 5.1	263.9 ± 5.84	−12.42 to 27.11	−6.673 to 32.86
Cluster Prominence	17372 ± 16.34	17134 ± 44.08	17036 ± 50.17	96.26 to 379.2 *	194.3 to 477.2 *
Cluster Shade	825.8 ± 42.54	819.7 ± 37.53	807.4 ± 40.61	−137.6 to 149.6	−125.2 to 162.0
Contrast	47.53 ± 1.99	45.03 ± 1.74	42.13 ± 1.78	−4.076 to 9.062	−1.166 to 11.97
Correlation	0.005 ± 0.0005	0.0005 ± 0.0003	0.05 ± 0.003	−0.0077 to 0.0076	−0.0531 to −0.0378 *
Energy	0.45 ± 0.006	0.42 ± 0.01	0.41 ± 0.01	−0.0283 to 0.0777	−0.0093 to 0.0968
Entropy	2.33 ± 0.02	2.41 ± 0.1	2.3 ± 0.11	−0.4098 to 0.2388	−0.2971 to 0.3515
Homogeneity	0.67 ± 0.01	0.65 ± 0.01	0.63 ± 0.01	−0.0287 to 0.0726	−0.0028 to 0.0985

* Significant difference.