Table 8.

GLSZM-based radiomic features for real and synthetic T2W for CycleGAN and DC²Anet models.

Features	Real T2W	Synthetic T2W-CycleGAN	Synthetic T2W-DC2Anet	95% CI of Diff
	Mean ± SE	Mean ± SE	Mean ± SE	Real T2W vs. Synthetic T2W-CycleGAN	Real T2W vs. Synthetic T2W-DC2Anet
Grey Level Mean	8.92 ± 0.38	9.49 ± 0.48	9.2 ± 0.48	−2.191 to 1.049	−1.905 to 1.336
Grey Level Nonuniformity	1.26 ± 0.02	1.4 ± 0.04	1.38 ± 0.03	−0.2608 to −0.0051 *	−0.2419 to 0.0137
Grey Level Variance	42.32 ± 0.57	43.40 ± 1.47	42.5 ± 1.372	−5.407 to 3.232	−4.504 to 4.134
High Grey Level Emphasis	136.1 ± 4.6	139.1 ±10.21	137.6 ± 10.27	−34.25 to 28.30	−32.82 to 29.73
Large Zone Emphasis	121.8 ± 8.08	119.9 ± 7.38	121.6 ± 7.41	−25.29 to 29.12	−27.03 to 27.38
Large Zone High Grey Level Emphasis	240.6 ± 4.04	245.6 ± 3.71	249.1 ± 3.56	−18.50 to 8.430	−22.00 to 4.930
Large Zone Low Grey Level Emphasis	152.2 ± 2.93	145.4 ± 5.44	135.1 ± 4.12	−8.474 to 22.10	1.827 to 32.40 *
Low Grey Level Emphasis	0.18 ± 0.01	0.19 ± 0.009	0.18 ± 0.008	−0.0510 to 0.0237	−0.0451 to 0.0296

* Significant difference.