Table 9.

GLSZM-based radiomic features for real and synthetic FLAIR for CycleGAN and DC²Anet models.

Features	Real FLAIR	Synthetic FLAIR -CycleGAN	Synthetic FLAIR-DC2Anet	95% CI of Diff
	Mean ± SE	Mean ± SE	Mean ± SE	Real FLAIR vs. Synthetic FLAIR-CycleGAN	Real FLAIR vs. Synthetic FLAIR-DC2Anet
Grey Level Mean	10.13 ± 0.26	10.12 ± 0.25	9.6 ± 0.19	−0.860 to 0.874	−0.349 to 1.386
Grey Level Nonuniformity	1.34 ± 0.02	1.3 ± 0.05	1.21 ± 0.06	−0.139 to 0.206	−0.047 to 0.298
Grey Level Variance	45.95 ± 2.34	47.5 ± 1.39	46.13 ± 1.24	−7.729 to 4.629	−6.357 to 6.001
High Grey Level Emphasis	152.5 ± 2.33	152.4 ± 2.66	141.3 ± 3.24	−9.836 to 9.940	1.322 to 21.10 *
Large Zone Emphasis	146.6 ± 9.91	142.8 ± 8	143.5 ± 8.1	−27.19 to 34.78	−27.88 to 34.09
Large Zone High Grey Level Emphasis	333.9 ± 8.78	331 ± 6.32	323.4 ± 7.4	−24.08 to 29.90	−16.49 to 37.49
Large Zone Low Grey Level Emphasis	147.8 ± 9.1	146 ± 8.18	119 ± 5.88	−26.05 to 29.57	0.995 to 56.61 *
Low Grey Level Emphasis	0.17 ± 0.007	0.18 ± 0.006	0.18 ± 0.005	−0.035 to 0.011	−0.032 to 0.014

* Significant difference.