Table 2.
Intergroup analysis of interim (week 2) rs–fMRI brain scans (right caudate nucleus as the seed region).
| Olfactory Cortical Network Regions | Cluster Size | Peak z Value |
|---|---|---|
| Combination group vs. standard care group | ||
| Right gyrus rectus | 21 | 6.4 |
| Combination group vs. control group | ||
| Left anterior cingulate cortex | 38 | 5.0 |
| Right anterior cingulate cortex | 7 | 4.2 |
| Left superior temporal gyrus | 28 | 5.2 |
| Standard care group vs. control group | ||
| Left anterior cingulate cortex | 24 | 4.8 |
| Left superior temporal gyrus | 20 | 6.0 |
Two-sample t test. GRF correction (voxel-level p < 0.010, cluster-level p < 0.050). rs–fMRI = resting-state functional magnetic resonance imaging. Combination = oral vitamin A in combination with aerosolised diffuser olfactory training (OT). Control= clinical observation. Standard care = OT alone.