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. 2023 Jun 30;13(7):1014. doi: 10.3390/brainsci13071014

Table 3.

Intergroup analysis of rs–fMRI brain scans (left caudate nucleus as the seed region).

Interim Assessment (Week 2) End-of-Treatment Assessment (Week 4)
OCN Regions Cluster Size Peak z Value OCN Regions Cluster Size Peak z Value
Combination group vs. control group
Right medial frontal gyrus 23 5.6 Left inferior frontal gyrus 21 4.2
Standard care group vs. control group
Right superior temporal gyrus 22 6.1 - - -

Two-sample t test. GRF correction (voxel-level p < 0.010, cluster-level p < 0.050). rs–fMRI = resting-state functional magnetic resonance imaging. OCN = olfactory cortical network. Combination = oral vitamin A in combination with aerosolised diffuser olfactory training (OT). Control= clinical observation. Standard care = OT alone.