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Apigetrin caused apoptosis in HepG2 cells. (a) To quantify apigetrin-induced apoptosis in HepG2 cells, double staining was performed at indicated concentrations (0, 50, and 100 µM) for 48 h. The data are presented as the mean ± standard error of mean (SEM) * p < 0.05, *** p < 0.001. (b) DAPI staining was performed to observe fragmented chromatin under a fluorescence microscope.
