Table 2.
Biomarkers predicting the effectiveness of midodrine hydrochloride in pediatric postural orthostatic tachycardia syndrome.
| Biomarkers | Cut-Off Value | Predictive Sensitivity (%) | Predictive Specificity (%) | References |
|---|---|---|---|---|
| Erythrocytic H2S production [nmol/(min·108 RBC)] | >27.1 | 78.9 | 77.8 | Yang et al. [60] |
| Plasma copeptin (pmol/L) | >10.482 | 81.3 | 76.5 | Zhao et al. [61] |
| Plasma MR-proADM (pg/L) | >61.5 | 100 | 71.6 | Zhang et al. [62] |
| Flow-mediated dilation (%) | >9.85 | 71.6 | 77.8 | Liao et al. [63] |
| ΔBP (mmHg) | ΔSBP < 0 | 60 | 80 | Deng et al. [64] |
| ΔDBP < 6.5 | 63 | 92 |
RBC, red blood cell; MR-proADM, mid-regional pro-adrenomedullin; Δ, change; BP, blood pressure; SBP, systolic blood pressure; DBP, diastolic blood pressure.