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. 1999 Oct;181(20):6441–6448. doi: 10.1128/jb.181.20.6441-6448.1999

TABLE 1.

Identification of genes encoding lipid particle proteinsa

No. Gene or ORF designation Function [hypothetical]b MW pI ORF Reference
1 FAA1 Long-chain fatty acid CoA ligase (for degradation or incorporation in PL) 77,866 7.70 YOR317c 23
2 FAT1 Very long-chain fatty acid activator; fatty acid transport protein (exogenous long-chain fatty acids) 71,700 8.40 YBR041c 10, 40
3 FAA4 Long-chain fatty acid CoA ligase (for degradation or incorporation into PL) 77,267 6.33 YMR246w 22
4 ERG7 Lanosterol synthase 83,318 6.30 YHR072w 4
5 YMR313c Unknown 73,612 8.74 YMR313c
6 TGL1 [Triacylglycerol lipase] 62,979 6.60 YKL140w 1
7 ERG1 Squalene epoxidase 55,120 6.27 YGR175c 19, 28
8 YBR177c [UFP007 family (not characterized); weak homologue to probable membrane receptor] 51,255 7.84 YBR177c
9 YOR059c [Lipase serine active site] 51,114 9.20 YOR059c
10 YIM1 [Homologue to mitochondrial inner membrane protease] 41,651 8.24 YMR152w
11 ERG6 Sterol-Δ24-methyltransferase 43,421 5.59 YML008c 27
12 YDL193w [Weak homologue to Ca2+ channel protein] 42,555 6.73 YDL193w
13 TDH1 GAPDH 35,619 8.41 YJL052w 32
TDH2 35,715 YJR009c
TDH3 35,615 YGR192c
14 YJU3 [Lysophospholipase] 35,549 8.55 YKL094w 12
15 YIM4 [Oxidoreductase (short-chain dehydrogenase or reductase family)] 32,822 9.34 YIL124w
16 YKR0456 Unknown 31,246 8.85 YKR046c
SLC1c 1-acylglycerol-3-phosphate acyltransferase 33,903 9.76 YDL052c 3, 34
a

MW, molecular weight; pI, isoelectric point; PL, phospholipid. 

b

Functions in brackets are hypothetical. 

c

The gene product of SLC1 was not detected during the mass spectrometric approach described in this work but was characterized earlier by biochemical and molecular biological means.