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. 2023 Jul 21;15(14):3711. doi: 10.3390/cancers15143711

Table 4.

Hematological toxicity for cholangiocarcinoma patients receiving either gemcitabine/cisplatin alone (30 patients, referred to as controls) or in combination with silmitasertib (87 patients, referred to as Silmitasertib). The results are presented as the number of patients with the percentage of patients given in parentheses [114].

Toxicity Anemia Thrombocytopenia Neutropenia
Silmitasertib Controls Silmitasertib Controls Silmitasertib Controls
All grades 34 (39%) 9 (30%) 24 (28%) 2 (7%) 27 (31%) 7 (23%)
Grade ≥ 3 17 (20%) 5 (17%) 11 (12%) 1 (3%) 20 (23%) 6 (20%)