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. 2023 Aug 1;133(15):e166954. doi: 10.1172/JCI166954

Figure 1. MoMFs and aHSCs are the major cell types encapsulating necrotic lesions after ConA-induced liver injury.

Figure 1

C57BL/6 mice were treated with 12 mg/kg ConA. Liver samples were collected 24, 48, 72, and 96 hours after ConA treatment. (A) Liver sections were stained with CD45 antibody and H&E. Representative images are shown (n = 5). (B and C) Multiplex immunofluorescent staining of several cell markers was performed on liver sections with necrotic lesions. Representative images are shown in B (n = 5). Quantification of number for each cell type identified in the border areas (indicated by dash lines) of necrotic regions is shown in C. The number and percentage of each type of cells are represented as means ± SD (n = 5). N, necrotic area.