Table 1.
Demographic profile and association of laboratory data with different studied participants.
| Parameters | Sepsis (n = 30) |
Control Arm | p Value | |
|---|---|---|---|---|
| Non-Sepsis (n = 23) |
Healthy (n = 30) |
|||
| Age(year) | 58 (13) | 49 (16) | 34 (13) | |
| Gender | ||||
| Female | 14 (46.7%) | 9 (39.1%) | 10 (33.3%) | |
| Male | 16 (53.3%) | 14 (60.9%) | 20 (66.7%) | |
| Blood Culture | ||||
| Positive | 7 (23.3%) | 0 | NA | |
| Negative | 23 (76.7%) | 23 (100%) | NA | |
| Clinical Outcome | ||||
| Death | 10 (33.3%) | 0 | NA | |
| Discharged | 20 (66.7%) | 23 (100%) | NA | |
| Laboratory Results | ||||
| SOFA | 7.10 (3.02) | 0.96 (0.21) | 0.00 (0.00) | <0.001 |
| CRP (mg/L) | 142.60 (47.85) | 75.84 (57.69) | 0.50 (0.00) | <0.001 |
| PCT (ng/mL) | 26.45 (36.63) | 0.25 (0.11) | 0.10 (0.00) | <0.001 |
| IL-6 (pg/mL) | 59.02 (42.07) | 28.34 (37.17) | 1.56 (0.00) | <0.001 |
| TWBC (103/μL) | 13.82 (5.50) | 13.00 (4.99) | 7.05 (1.87) | <0.001 |
| NEUT# (103/μL) | 12.26 (5.71) | 10.88 (4.56) | 3.85 (1.37) | <0.001 |
| NEUT-GI (SI) | 150.80 (5.97) | 153.33 (4.98) | 149.13 (2.80) | 0.008 |
| NEUT-RI (FI) | 56.49 (10.36) | 52.20 (6.15) | 45.61 (1.89) | <0.001 |
| IG# (103/μL) | 0.47 (0.77) | 0.17 (0.22) | 0.05 (0.03) | 0.004 |
| MONO# (103/μL) | 0.73 (0.31) | 0.85 (0.53) | 0.53 (0.17) | 0.004 |
| LYMPH# (103/μL) | 1.04 (0.52) | 1.18 (0.54) | 2.30 (0.57) | <0.001 |
| RE-LYMP (103/μL) | 0.11 (0.11) | 0.06 (0.05) | 0.04 (0.03) | 0.001 |
| AS-LYMP (cells/μL) | 0.05 (0.07) | 0.02 (0.02) | 0.01 (0.02) | 0.014 |
| PLT# (103/μL) | 197.77 (109.92) | 282.65 (123.12) | 292.83 (78.68) | 0.001 |
| IPF % | 5.69 (4.32) | 3.27 (2.06) | 4.09 (2.45) | 0.021 |
| Delta-He (pg) | 0.14 (3.62) | 2.01 (2.19) | 2.85 (1.73) | 0.001 |
| NE-WX (ch) | 338.57 (33.96) | 314.65 (17.00) | 314.77 (10.94) | <0.001 |
| NE-WY (ch) | 750.87 (175.04) | 673.78 (91.44) | 601.30 (24.55) | <0.001 |
| NE-WZ (ch) | 659.67 (48.42) | 606.22 (26.48) | 634.93 (27.51) | <0.001 |
| RE-MONO# (103/μL) | 0.015 (0.030) | 0.003 (0.007) | 0.004 (0.005) | 0.037 |
All the variables were analysed by one-way ANOVA. p < 0.05 was statistically significant. SD, standard deviation; df, degree of freedom; SOFA, Sequential Organ Failure Assessment; CRP, C-reactive protein; PCT, procalcitonin; IL-6, interleukin 6; TWBC, total white blood cell count; NEUT#, neutrophil count; NEUT-GI, neutrophil granularity intensity; NEUT-RI, neutrophil reactivity intensity; IG#, immature granulocyte count; MONO, monocyte count; LYMPH#, lymphocyte count; RE-LYMPH, reactive lymphocyte; AS-LYMPH, antibody synthesizing lymphocyte; PLT, platelet count; IPF%, immature platelet fraction in percentage; Delta-He, delta haemoglobin; NE-WX, the width of the lateral scattered light distribution width; NE-WY, the width of the fluorescent light distribution of the neutrophil scattergram; NE-WZ, the forward scattered light distribution; RE-MONO, reactive monocyte; ICIS, intensive care infection score.