Figure 6.

Policosanol induces regeneration of zebrafish fins. (a) Caudal fin rays of adult zebrafish that have been amputated at day 0. ARS staining to reveal mineralization of the caudal fin rays of adult zebrafish (top, total caudal fin rays; bottom, enlarged part). (b) Caudal fin rays of adult zebrafish were cut, and the fish were treated with either policosanol for 6 days (+: 50 μg/mL and ++: 100 μg/mL). (c) Caudal fin rays of adult zebrafish were quantified and compared between the control and policosanol-treated group. Scale bar, 200 μm. *** p < 0.001 compared with the control zebrafish. Data represent the mean ± SD of three individual experiments.